You Asked For It… You Got It… The Introduction Of Skin Aging And How StriCura Might Be Your Best Anti-Aging Solution

The natural aging of you skin results in decreased production and an increased degradation of important proteins like collagen, fibronectin, elastin and laminin. This extracellular matrix, in addition to providing structural support, also influences cellular behaviors like differentiation and proliferation. These functions are controlled through small peptides derived from proteolytic degradation of extracellular matrix proteins. These matrikines act as signal proteins between matrix component and cell wall receptors. Various peptides affect the aging process by modulating collagen homeostasis.

An Overview Of One Of The Active Ingredients In StriCura… Palmitoyl Tripeptide-5

Palmitoyl Tripeptide-5 (palmitoyl-lysyl-valyl-lysine) is a synthetic signal peptide that induces the release of active transforming growth factor-β (TGF-β). Simply speaking, palmitoyl tripeptide-5 mimics the human body's own mechanisms and speeds up the synthesis of collagen in the skin. 

The Science Behind Palmitoyl Tripeptide-5

Animal studies have indicated that palmitoyl tripeptide-5 may increase collagen synthesis. In vitro studies have shown that palmitoyl tripeptide-5 can prevent collagen breakdown by interfering with MMP1 and MMP3 collagen degradation. Furthermore, in a controlled trial, 60 healthy volunteers received 2.5% palmitoyl tripeptide-5 versus a placebo cream twice daily for 84 days. Palmitoyl tripeptide-5 significantly decreased the average relief and maximum relief parameters by 12%. 

Palmitoyl tripeptide-5 can be used as active ingredient in anti-ageing skincare products, as it can address extracellular matrix damage, inhibit skin inflammation and firm and moisturize the skin. If you have problems with stretch marks, wrinkles or aging skin, StriCura might be your best answer.

References:

1. Schagen, S. K. (2017). Topical peptide treatments with effective anti-aging results. Cosmetics, 4(2), 16.
2. Zhang, L., & Falla, T. J. (2009). Cosmeceuticals and peptides. Clinics in dermatology, 27(5), 485-494.
3. Son, E. D., Min, D. J., Chang, H. K., Choi, H. J., Seong, A. C., Kim, J. H., & Lee, T. R. (2018). U.S. Patent No. 9,867,772. Washington, DC: U.S. Patent and Trademark Office.
4. G Gorouhi, F., & Maibach, H. I. (2009). Role of topical peptides in preventing or treating aged skin. International journal of cosmetic science, 31(5), 327-345.